2022
| Structure and biosynthesis of the ribosomal lipopeptide antibiotic albopeptins. |
|---|
| H. Oikawa, Y. Mizunoue, T. Nakamura, E. Fukushi, Y. Jiang, T. Ozaki, A. Minami |
| BBB, In press |
| DOI: 10.1093/bbb/zbac039
|
| Biosynthetic machineries of anthraquinones and bisanthraquinones in Talaromyces islandicus. |
| M. Fukaya, T. Ozaki, A. Minami, H. Oikawa |
| BBB, In press |
| DOI: 10.1093/bbb/zbac009
|
2021
| Heterologous expression of a polyketide synthase ACRTS2 in Aspregillus oryzae produces host selective ACR-toxins: Co-production of minor metabolites. |
|---|
| A. Kotani, T. Ozaki, J. Takino, S. Mochizuki, K. Akimitsu, A. Minami, H. Oikawa |
| BBB, 2022, 86, 3, 287-293 |
| DOI: 10.1093/bbb/zbab214
Biosynthetic Studies of Phomopsins Unveil Posttranslational Installation of Dehydroamino Acids by UstYa Family Proteins. |
| K. Sogahata, T. Ozaki, Y. Igarashi, Y. Naganuma, C. Liu, A. Minami, H. Oikawa |
| Angew Chem Int Ed Engl, 2021, 60, 49, 25729-25734 |
| DOI: 10.1002/anie.202111076 and 10.1002/ange.202111076 |
|
Biochemistry-guided prediction of the absolute configuration of fungal reduced polyketides. |
| J. Takino, A. Kotani, T. Ozaki, W. Peng, J. Yu, Y. Guo, S. Mochizuki, K. Akimitsu, M. Hashimoto, T. Ye, A. Minami, H. Oikawa |
| Angew Chem Int Ed Engl, 2021, 60, 43, 23403-23411 |
| DOI: 10.1002/anie.202110658 and 10.1002/ange.202110658
|
| Biosynthesis of Cyclochlorotine: Identification of the Genes Involved in Oxidative Transformations and Intramolecular O,N- Transacylation. |
| Y. Jiang, T. Ozaki, C. W. Liu, Y. Igarashi, Y. Ye, S. Tang, T. Ye, J. Maruyama, A. Minami, H. Oikawa |
| Org Lett, 2021, 23, 7, 2616–2620 |
| DOI: 10.1021/acs.orglett.1c00525
Genome-based discovery of enantiomeric pentacyclic sesterterpenes catalyzed by the fungal bifunctional terpene synthases. |
| L. Jiang, X. Zhang, Y. Sato, G. Zhu, A. Minami, W. Zhang, T. Ozaki, B. Zhu, Z. Wang, X. Wang, K. Lv, J. Zhang, Y. H. Wang, S. S. Gao, C. Liu, T. Hsiang, L. Zhang, H. Oikawa, X. Liu |
| Org Lett, 2021, 23, 12, 4645-4650 |
| DOI: /10.1021/acs.orglett.1c01361
【著書】 |
| 麹菌が切り拓く天然物化学～麹菌を利用した生物活性天然物の生産 |
| 南 篤志、尾﨑太郎、及川英秋 |
| 発酵・醸造食品の最前線Ⅱ, シーエムシー出版, In press
|
2020
| Heterologous production of fungal natural products: Reconstitution of biosynthetic gene clusters in model host Aspergillus oryzae. |
|---|
| H. Oikawa |
| Proc Jpn Acad Ser B Phys Biol Sci, 2020, 96, 420-430 |
| DOI: 10.2183/pjab.96.031
|
| Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes. |
| A. Minami, T. Ugai, T. Ozaki, H. Oikawa |
| Sci Rep, 2020, 10, 13556 |
| DOI: 10.1038/s41598-020-70177-w
|
| Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton. |
| Y. Jiang, T. Ozaki, M. Harada, T. Miyasaka, H. Sato, K. Miyamoto, J. Kanazawa, C. Liu, J. Maruyama, M. Adachi, A. Nakazaki, T. Nishikawa, M. Uchiyama, A. Minami, H. Oikawa |
| Angew Chem Int Ed, 2020, 59, 17996–18002 |
| DOI: 10.1002/anie.202007280
|
| Fungal-derived Brevianamide assembly by a stereoselective semi-pinacolase. |
| Y. Ye, L. Du, X. Zhang, S. A. Newmister, M. McCauley, J. V. Alegre-Requena, W. Zhang, S. Mu, A. Minami, A. E. Fraley, M. L. Adrover-Castellano, N. A. Carney, V. V. Shende, F. Qi, H. Oikawa, H. Kato, S. Tsukamoto, R. S. Paton, R. M. Williams, D. H. Sherman, S. Li |
| Nat Catal, 2020, 3, 497–506 |
| DOI: 10.1038/s41929-020-0454-9 |
| Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin. |
| T. Shiina, T. Ozaki, Y. Matsu, S. Nagamine, C. Liu, M. Hashimoto, A. Minami, H. Oikawa |
| Org Lett, 2020, 22, 5, 1997-2001 |
| DOI: 10.1021/acs.orglett.0c00340
|
| Total synthesis of alkaloids using both chemical and biochemical methods. |
| R. Tanifuji, A. Minami, H. Oguri, H. Oikawa |
| Nat Prod Rep, 2020, 37, 1098-1121 |
| DOI: 10.1039/c9np00073a
|
| Reconstitution of biosynthetic machinery of fungal natural products in heterologous hosts. |
| H. Oikawa |
| Biosci Biotechnol Biochem, 2020, 84, 3, 433-444 |
| DOI: 10.1080/09168451.2019.1690976
|
| FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. |
| L. Gao, C. Su, X. Du, R. Wang, S. Chen, Y. Zhou, C. Liu, X. Liu, R. Tian, L. Zhang, K. Xie, S. Chen, Q. Guo, L. Guo, Y. Hano, M. Shimazaki, A. Minami, H. Oikawa, N. Huang, K. N. Houk, L. Huang, J. Dai, X. Lei |
| Nat Chem, 2020, 12, 620–628 |
| DOI: https://doi.org/10.1038/s41557-020-0467-7
|
| Biosynthetic machinery of 6-hydroxymellein derivatives leading to cyclohelminthols and palmaenones. |
| T. Ugai, A. Minami, S. Tanaka, T. Ozaki, C. Liu, H. Shigemori, M. Hashimoto and H. Oikawa |
| ChemBioChem, 2020, 21, 360-367 |
| DOI: 10.1002/cbic.201900404 |
|
|
| 【著書】 |
| Biosynthesis of Indole Diterpenes |
| C. Liu, A. Minami, T. Ozaki, and H. Oikawa |
| Comprehensive Natural Products Ⅲ: Chemistry and Biology, H.-W. Liu and T. Begley, Ed., Elsevier, 2020, 2, 446-466
|
| 【総説・解説など】 |
| 糸状菌由来生物活性天然物の全生合成 |
| 南 篤志、尾﨑太郎、及川英秋 |
| ファインケミカル, 2020, 49, 3, 19-24
|
2019
| Efficient reconstitution of Basidiomycota diterpene erinacine gene cluster in Ascomycota host Aspergillus oryzae based on genomic DNA sequences. Liu, C.; Minami, A.; Ozaki, T.; Wu, J.; Kawagishi, H.; Maruyama, J.; Oikawa, H.; J. Am. Chem. Soc. 2019, 141, 39, 15519-15523 DOI: 10.1021/jacs.9b08935
|
|---|
| Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase. Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.; Biosci Biotechnol Biochem. 2019, 83(2), 192-201 DOI: 10.1080/09168451.2018.1536518 |
| BBB Awards for Excellence to Authors (2019) Vol. 83 受賞
Ascomycota Aspergillus oryzae is an efficient expression host for production of Basidiomycota terpenes using genomic DNA sequences. Nagamine, S.; Nishishita, J.; Kozaki, T.; Sogahata, K.; Sato, Y.; Minami, A.; Liu, C.; Ozaki, T.; Schmidt-Dannert, C.; Maruyama, J.; Oikawa, H.; Appl. Environ. Microbiol., 2019. DOI: 10.1128/AEM.00409-19 |
| Heterologous production of asperipin-2a: Proposal for sequential oxidative macrocyclization by a fungi-specific DUF3328 oxidase. Ye, Y.; Ozaki, T.; Umemura, M.; Liu, C.; Minami, A.; Oikawa, H.; Org. Biomol. Chem. 2019, 17, 39-43 DOI: 10.1039/C8OB02824A
|
| Zn(OTf)2 mediated annulations of <i>N</i>-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds. Yorimoto, S.; Tsubouchi, A; Mizoguchi, H.; Oikawa, H.; Tsunekawa, Y.; Ichino, T.; Maeda, S.; Oguri, H.; Chem. 2019, 10, 5686-5698 DOI: 10.1039/C9SC01507H
|
| Elucidation of biosynthetic pathway of a plant hormone abscisic acid in phytopathogenic fungi. Takino, J.; Kozaki, T.; Ozaki, T.; Liu, C.; Minami, A.; Oikawa, H.; Biosci. Biotech. Biochem. 2019, 83, 1642-1649 DOI: 10.1080/09168451.2019.1618700
|
| Generation of C5-desoxy analogs of tetrahydroisoquinoline alkaloids exhibiting potent DNA alkylating ability. Tanifuji, R.; Tsukakoshi, K.; Ikebukuro, K.; Oikawa, H.; Oguri, H.; Bioorg. Med. Chem. Lett. 2019, 29, 1807-1811 https://doi.org/10.1016/j.bmcl.2019.05.009
|
| 【著書】 |
| Sesterterpene Biosynthesis: Cyclization Mechanisms and Oxidative Modifications |
| A. Minami, T. Ozaki, C. Liu, and H. Oikawa |
| Comprehensive Natural Products Ⅲ: Chemistry and Biology, H.-W. Liu and T. Begley, Ed., Elsevier, Vol. 1, 553-576 (2020) |
|
【総説・解説など】 |
| 糸状菌による植物ホルモンアブシジン酸の生合成：新奇な環化酵素の発見とその環化機構の解明、南篤志、尾﨑太郎、劉成偉、及川英秋 バイオサイエンスとインダストリー、Vol. 77, NO2, 136-138 (2019)
|
2018
| Unveiling Biosynthesis of the Phytohormone Abscisic Acid in Fungi: Unprecedented Mechanism of Core Scaffold Formation Catalyzed by an Unusual Sesquiterpene Synthase. Takino, J.; Kozaki, T.; Sato, Y.; Liu, C.; Ozaki, T.; Minami, A.; Oikawa, H.; J. Am. Chem. Soc. 2018, 140, 12392–12395 DOI: 10.1021/jacs.8b08925
|
|---|
| Enzymatic formation of a skipped methyl-substituted octaprenyl side chain of longestin (KS-505a): Involvement of homo-IPP as a common extender unit. Ozaki, T.; Shinde, S. S.; Gao, L.; Okuizumi, R.; Liu, C.; Ogasawara, Y.; Lei, X.; Dairi, T.; Minami, A.; Oikawa, H.; Angew. Chem. Int. Ed. Engl. 2018, 57, 6629-6632 DOI: 10.1002/anie.201802116 |
| Chemo-enzymatic Total Syntheses of Jorunnamycin A, SaframycinA, and N‑Fmoc Saframycin Y3. Tanifuji, R.; Koketsu, K.; Takakura, M.; Asano, R.; Minami, A.; Oikawa, H.; Oguri, H.; J. Am. Chem. Soc. 2018, 140, 10705–10709 DOI: 10.1021/jacs.8b07161
|
| Cyclopentane forming di-/sesterterpene synthases: widely distributed enzymes in bacteria, fungi and plants. Minami, A.; Ozaki, T.; Liu, C.; Oikawa, H.; Nat. Prod. Rep. 2018, 35, 1330-1346 DOI: 10.1039/C8NP00026C
|
| Total Biosynthesis of Brassicicenes: Identification of a Key Enzyme for Skeletal Diversification. Tazawa, A.; Ye, Y.; Ozaki, T.; Liu, C.; Ogasawara, Y.; Dairi, T.; Higuchi, Y.; Kato, N.; Gomi, K.; Minami, A.; Oikawa, H.; Org. lett. 2018, 20, 6178-6182 DOI: 10.1021/acs.orglett.8b02654
|
| Design and De Novo Synthesis of 6-Aza-artemisinins. Bonepally, K. R.; Hiruma, T.; Mizoguchi, H.; Ochiai, K.; Suzuki, S.; Oikawa, H.; Ishiyama, A.; Hokari, R.; Iwatsuki, M.; Otoguro, K.; O̅mura, S.; Oguri, H.; Organic letters. 2018, 20, 4667-4671 DOI: 10.1021/acs.orglett.8b01987
|
| Heterologous biosynthesis of fungal indole sesquiterpene sespendole. Kudo, K; Liu, C.; Matsumoto, T.; Minami, A.; Ozaki, T.; Toshima, H.; Gomi, K.; Oikawa, H.; ChemBioChem 2018, 19, 1492-1497 DOI: 10.1002/cbic.201800187 |
| Theoretical Study of Sesterfisherol Biosynthesis: Computational Prediction of Key Amino Acid Residue in Terpene Synthase. Sato, H.; Narita, K.; Minami, A.; Yamazaki, M.; Wang, C.; Suemune, H.; Nagano, S.; Tomita, T.; Oikawa, H.; Uchiyama, M.; Sci. Rep. 2018, 8, 2473 DOI: 10.1038/s41598-018-20916-x
|
| Total biosynthesis of antiangiogenic agent (-)-terpestacin by artificial reconstitution of the biosynthetic machinery in Aspergillus oryzae. Narita, K.; Minami, A.; Ozaki, T.; Liu, C.; Kodama, M.; Oikawa, H.; J. Org. Chem. 2018, 83, 7042-7048 DOI: 10.1021/acs.joc.7b03220 |
|
Identification of novel sesterterpenes by genome mining of phytopathogenic fungi Phoma and Colletotrichum sp. Gao, L.; Narita, K.; Ozaki, Kumakura, N.; Gan, P.; Minami, A.; Liu, C.; Lei, X.; Shirasu, K.; Oikawa, H.; Tetrahedron Lett. 2018, 59, 1136-1139 DOI: 10.1016/j.tetlet.2018.02.022 |
| Subcellular localization of aphidicolin biosynthetic enzymes heterologously expressed in Aspergillus oryzae. Ban, A.; Tanaka, M.; Fujii, R.; Minami, A.; Oikawa, H.; Shintani, T.; Gomi, K.; Biosci. Biotech. Bioch. 2018, 82, 139-147 DOI: 10.1080/09168451.2017.1399789
|
| Biosynthetic study of conidiation-inducing factor conidiogenone: Heterologous production and cyclization mechanism of a key bifunctional diterpene synthase. Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.; Biosci. Biotechnol. Biochem. 2018, DOI: 10.1080/09168451.2018.1536518
【総説・解説など】 |
| ゲノム情報を用いたC20/C25テルペン環化酵素遺伝子の網羅的発現による新規天然物の生産 |
| 南篤志、尾﨑太郎、劉成偉、及川英秋 |
| バイオサイエンスとインダストリー、Vol76.NO1,(2018)
【著書】 |
| 書名：酵母菌・麹菌・乳酸菌の産業応用展開 |
| 麹菌を宿主としたカビの二次代謝産物の生産 |
| 南篤志、劉成偉、尾﨑太郎、及川英秋 |
| シーエムシー出版 |
2017
| Focused Genome Mining of Structurally Related Sesterterpenes: Enzymatic Formation of Enantiomeric and Diastereomeric Products. Narita, K.; Sato, H.; Minami, A.; Kudo, K.; Gao, L.; Liu, C.; Ozaki, T.; Kodama, M.; Lei, X.; Taniguchi, T.; Monde, K.; Yamazaki, M.; Uchiyama, M.; Oikawa, H.; Org. Lett. 2017, 19, 6696-6699 DOI: 10.1021/acs.orglett.7b03418
|
|---|
| Stepwise cyclopropanation on the polycyclopropanated polyketide formation in jawsamycin biosynthesis. Hiratsuka, T.; Suzuki, H.; Minami, A.; Oikawa, H.; Org. Biomol. Chem. 2017,15,1076-1079 DOI: 10.1039/C6OB02675C
|
| Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo. Ozaki, T.; Yamashita, K..; Goto, Y.; Shimomura, M.; Hayashi, S.; Asamizu, S.; Sugai, Y.; Ikeda, H.; Suga, H.; Onaka, H.; Nat. Commun. 2017, 8, 14207-14207 DOI:10.1038/ncomms14207 |
| Cyclization mechanism of phomopsene synthase: mass spectrometry based analysis of various site-specifically labeled terpenes. Shinde, S. S.; Minami, A.; Chen, Z.; Tokiwano, T.; Toyomasu, T.; Kato, N.; Sassa, T.; Oikawa, H.; J. antibiot. 2017,70,632-638 DOI: 10.1038/ja.2017.27
|
| Biosynthetic machinery of diterpene pleuromutilin isolated from basidiomycete fungi. Yamane, M.; Minami, A.; Liu, C.; Ozaki, T.; Takeuchi, I.; Tsukagoshi, T.; Tokiwano, T.; Gomi, K.; Oikawa, H.; ChemBioChem 2017, 18, 2317-2322 DOI: 10.1002/cbic.201700434 |
2016
| Discovery and Total Synthesis of Streptoaminals: Antimicrobial [5,5]-Spirohemiaminals from the Combined-Culture of Streptomyces nigrescens and Tsukamurella pulmonis. Sugiyama, R.; Nishimura, S.; Ozaki, T.; Asamizu, S.; Onaka, H.; Kakeya, H.; Angew. Chemi. Int. Edit. 2016, 55, 10278-10282 DOI: 10.1002/anie.201604126
|
|---|
| Unveiling the Biosynthetic Pathway of the Ribosomally Synthesized and Post-translationally Modified Peptide Ustiloxin B in Filamentous Fungi. Ye, Y.; Minami, A.; Igarashi, Y.; Izumikawa, M.; Umemura, M.; Nagano, N.; Machida, M.; Kawahara, T.; Shin-ya, K.; Gomi, K.; Oikawa, H.; Angew. Chem. Int. Ed. 2016, 55, 8072-8075 DOI: 10.1002/anie.201602611
|
| Multiple Oxidative Modifications in the Ophiobolin Biosynthesis: P450 Oxidations Found in Genome Mining. Narita, K.; Chiba, R.; Minami, A.; Kodama, M.; Fujii, I.; Gomi, K.; Oikawa, H.Org. Lett. 2016, 18, 1980-1983 DOI: 10.1021/acs.orglett.6b00552
|
| Biosynthesis of Shearinine: Diversification of a Tandem Prenyl Moiety of Fungal Indole Diterpenes. Liu, C. W.; Minami, A.; Dairi, T.; Gomi, K.; Scott, Barry, S.; Oikawa, H. Org. Lett. 2016, 18, 5026−5029 DOI: 10.1021/acs.orglett.6b02482
|
| Genome mining approach harnessing the cryptic gene cluster in Alternaria solani: Production of PKS-NRPS hybrid metabolite, didymellamide B. Ugai, T.; Minami, A.; Gomi, K.; Oikawa, H.; Tetrahedron Lett. 2016, 57, 2793-2796 DOI: 10.1016/j.tetlet.2016.05.043
|
| Insights into the Biosynthesis of Dehydroalanines in Goadsporin. Ozaki, T.; Kurokawa, Y.; Hayashi, S.; Oku, N.; Asamizu, S.; Igarashi, Y.; Onaka, H.; Chembiochem. 2016, 17, 218-223 DOI: 10.1002/cbic.201500541
|
| Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host. Fujii, R.; Ugai, T.; Ichinose, H.; Hatakeyama, M.; Kosaki, T.; Gomi, K.; Fujii, I.; Minami, A.; Oikawa, H. Biosci. Biotechnol. Biochem. 2016, 80, 426-431 DOI: 10.1080/09168451.2015.1104234.
|
| Catalytic asymmetric synthesis of the common amino acid component in the biosynthesis of tetrahydroisoquinoline alkaloids. Tanifuji, R.; Oguri, H.; Koketsu, K.; Yoshinaga, Y.; Minami, A.; Oikawa, H. Tetrahedron Lett. 2016, 57, 623-626 DOI:10.1016/j.tetlet.2015.12.110 |
|
|
| 【総説・解説など】 |
| Total Biosynthesis of Fungal Indole Diterpenes Using Cell Factories. Minami, A.; Liu, C.; Oikawa, H. Heterocycles. 2016, 92, 397-421 DOI: 10.3987/REV-15-830
|
| Recent advances of Diels–Alderases involved in natural product biosynthesis. Minami, A; Oikawa, H. J. Antibiot. 2016, 69, 500-506 DOI: 10.1038/ja.2016.67.
|
| Nature’s Strategy for Catalyzing Diels-Alder Reaction. Oikawa, H.; Cell Chem. Biol. 2016, 23, 429-430 DOI: 10.1016/j.chembiol.2016.04.002
Exploring the diversification mechanism of skeletal construction in representative natural product families. Oikawa, H.; Tang, Y.; J. Antibiot. 2016, 69, 471-472 DOI: 10.1038/ja.2016.69 |
2015
| Reconstitution of biosynthetic machinery for highly elaborated indole diterpene penitrem.Liu, C. W.; Tagami, K.; Minami, A.; Matsumoto, T.; Frisvad, J. C.; Suzuki, H.; Ishikawa,J.; Gomi, K.; and Oikawa, H. Angew. Chem. Int. Ed. 2015, 54, 5748-5752 DOI: 10.1002/anie.201502797
|
|---|
| Genome Mining for Sesterterpenes Using Bifunctional Terpene Synthases Reveals a Unified Intermediate of Di/Sesterterpenes.Ye, Y.; Minami, A.; Mandi, A.; Liu, C.; Taniguchi, T.; Kuzuyama, T.;Monde, K.; Gomi, K.; Oikawa, H. J. Am. Chem. Soc. 2015, 137, 11846-11853 DOI: 10.1021/jacs.5b08319
|
| Biosynthetic Study on Antihypercholesterolemic Agent Phomoidride: General Biogenesis of Fungal Dimeric Anhydrides.Fujii, R.; Matsu, Y.; Minami, A.; Nagamine, S.; Takeuchi, I.; Gomi, K.; Oikawa, H.Org. Lett. 2015, 17, 5658-5661 DOI: 10.1021/acs.orglett.5b02934
|
| Heterologous Expression of Highly Reducing Polyketide Synthase Involved in Betaenone Biosynthesis.Ugai, T.;Minami, A.; Fujii, R.; Tanaka, M.; Oguri, H.; Gomi, K.; Oikawa, H.Chem.Commun. 2015, 51, 1878-1881 DOI: 10.1039/C4CC09512J
|
| Minimum Information about a Biosynthetic Gene cluster.Medema, M. H.; Kottmann, R.; Yilmaz, P.; Cummings, M.; Biggins, J. B.; Blin, K.; de Bruijn, I.; Chooi, Y. H.; Claesen, J.; Coates, R. C.; Cruz-Morales, P.; Duddela, S.; Dusterhus, S.; Edwards, D. J.; Fewer, D. P.; Garg, N.; Geiger, C.; Gomez-Escribano, J. P.; Greule, A.; Hadjithomas, M.; Haines, A. S.; Helfrich, E. J. N.; Hillwig, M. L.; Ishida, K.; Jones, A. C.; Jones, C. S.; Jungmann, K.; Kegler, C.; Kim, H. U.; Kotter, P.; Krug, D.; Masschelein, J.; Melnik, A. V.; Mantovani, S. M.; Monroe, E. A.; Moore, M.; Moss, N.; Nutzmann, H. W.; Pan, G. H.; Pati, A.; Petras, D.; Reen, F. J.; Rosconi, F.; Rui, Z.; Tian, Z. H.; Tobias, N. J.; Tsunematsu, Y.; Wiemann, P.; Wyckoff, E.; Yan, X. H.; Yim, G.; Yu, F. G.; Xie, Y. C.; Aigle, B.; Apel, A. K.; Balibar, C. J.; Balskus, E. P.; Barona-Gomez, F.; Bechthold, A.; Bode, H. B.; Borriss, R.; Brady, S. F.; Brakhage, A. A.; Caffrey, P.; Cheng, Y. Q.; Clardy, J.; Cox, R. J.; De Mot, R.; Donadio, S.; Donia, M. S.; van der Donk, W. A.; Dorrestein, P. C.; Doyle, S.; Driessen, A. J. M.; Ehling-Schulz, M.; Entian, K. D.; Fischbach, M. A.; Gerwick, L.; Gerwick, W. H.; Gross, H.; Gust, B.; Hertweck, C.; Hofte, M.; Jensen, S. E.; Ju, J. H.; Katz, L.; Kaysser, L.; Klassen, J. L.; Keller, N. P.; Kormanec, J.; Kuipers, O. P.; Kuzuyama, T.; Kyrpides, N. C.; Kwon, H. J.; Lautru, S.; Lavigne, R.; Lee, C. Y.; Linquan, B.; Liu, X. Y.; Liu, W.; Luzhetskyy, A.; Mahmud, T.; Mast, Y.; Mendez, C.; Metsa-Ketela, M.; Micklefield, J.; Mitchell, D. A.; Moore, B. S.; Moreira, L. M.; Muller, R.; Neilan, B. A.; Nett, M.; Nielsen, J.; O'Gara, F.; Oikawa, H.; Osbourn, A.; Osburne, M. S.; Ostash, B.; Payne, S. M.; Pernodet, J. L.; Petricek, M.; Piel, J.; Ploux, O.; Raaijmakers, J. M.; Salas, J. A.; Schmitt, E. K.; Scott, B.; Seipke, R. F.; Shen, B.; Sherman, D. H.; Sivonen, K.; Smanski, M. J.; Sosio, M.; Stegmann, E.; Sussmuth, R. D.; Tahlan, K.; Thomas, C. M.; Tang, Y.; Truman, A. W.; Viaud, M.; Walton, J. D.; Walsh, C. T.; Weber, T.; van Wezel, G. P.; Wilkinson, B.; Willey, J. M.; Wohlleben, W.; Wright, G. D.; Ziemert, N.; Zhang, C. S.; Zotchev, S. B.; Breitling, R.; Takano, E.; Glockner, F. O. Nat. Chem. Biol. 2015, 11, 625-631 DOI:10.1038/nchembio.1890 |