{"id":15,"date":"2023-03-23T15:08:57","date_gmt":"2023-03-23T06:08:57","guid":{"rendered":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/?page_id=15"},"modified":"2026-01-22T13:29:21","modified_gmt":"2026-01-22T04:29:21","slug":"publications","status":"publish","type":"page","link":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/publications\/","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u7814\u7a76\u696d\u7e3e<\/h2>\n\n\n\n<ul class=\"wp-block-list icon\">\n<li><a href=\"#1\">\u539f\u8457\u8ad6\u6587<\/a><\/li>\n\n\n\n<li><a href=\"#2\">\u7dcf\u8aac\u30fb\u8457\u66f8<\/a><\/li>\n\n\n\n<li><a href=\"#3\">\u5b66\u4f1a\u767a\u8868<\/a><\/li>\n\n\n\n<li><a href=\"#4\">\u305d\u306e\u4ed6<\/a><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"1\">\u539f\u8457\u8ad6\u6587<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">2026<\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Design, synthesis, and structural analysis of an inhibitor of the gastric proton pump with a diaza-tricyclic skeleton<br>Umekubo, N., Hashizume, A., Saito, H., Kato, S., Kanai, C., Gopalasingam, C. C., Gerle, C., Shigematsu, H., *Yoshimori, A., *<strong><u>Abe, K.<\/u><\/strong>, *Yokoshima, S.<br><strong><em>Org. Biomol. Chem.<\/em><\/strong>, In press (2026) <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2026\/ob\/d5ob01828e\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1039\/d5ob01828e<\/a><\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\">2025<\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Cryo-EM Structure of the ATP11C Q79E Mutant Reveals the Structural Basis for Altered Phospholipid Recognition<br>Qian, Y., Gopalasingam, C. C., Gerle, C., Shigematsu, H., *<strong><u>Abe, K.<\/u><\/strong>, *Oshima, A.<br><strong><em>J. Biol. Chem.<\/em><\/strong>, Volume 302, Issue 1, 110935 (2025) <a href=\"https:\/\/doi.org\/10.1016\/j.jbc.2025.110935\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1016\/j.jbc.2025.110935<\/a><\/li>\n\n\n\n<li>A unique gating mechanism revealed by the cryo-EM structure of monomeric ATP9A flippase<br>*<strong><u>Abe, K.<\/u><\/strong>, Marimuthu, P., Qian, Y., Gopalasingam, C. C., Gerle, C., Shigematsu, H., Tanaka, K., Khandelia, H.<br><strong><em>J. Biol. Chem.<\/em><\/strong>, Volume 301, Issue 10, 110631 (2025) <a href=\"https:\/\/doi.org\/10.1016\/j.jbc.2025.110631\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1016\/j.jbc.2025.110631<\/a><\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\">2024<\/h4>\n\n\n\n<ol reversed class=\"wp-block-list\">\n<li>Molecular Structure of the Na+,K+-ATPase \u03b14\u03b21 Isoform in Its Ouabain-Bound Conformation <br>*<strong><u>Abe, K.<\/u><\/strong>, McDermott, J., Madapally, H.V., Marimuthu, P., Gopalasingam, C.C., Gerle, C., Shigematsu, H., Khandelia, H. &amp; *Blanco, G.<br><strong><em>Int. J. Mol. Sci.<\/em><\/strong>, 25(22), 12397 (2024) <a href=\"https:\/\/www.mdpi.com\/1422-0067\/25\/22\/12397\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.3390\/ijms252212397<\/a><\/li>\n\n\n\n<li>Human F-ATP synthase as a drug target<br>*Gerle, C., Jiko, C., Nakano, A., Yokoyama, K., Gopalasingam, C.C., Shigematsu, H., <strong><u>Abe, K.<\/u><\/strong> <br><em><strong>Pharmacol. Res<\/strong><\/em>., 209, 107423 (2024) <a href=\"https:\/\/doi.org\/10.1016\/j.phrs.2024.107423\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1016\/j.phrs.2024.107423<\/a><\/li>\n\n\n\n<li>Specific protonation of acidic residues confers K<sup>+<\/sup> selectivity to the gastric proton pump<br>Madapally, H.V., <strong><u>Abe, K.<\/u><\/strong>, Dubey, V. &amp; *Khandelia, H.<br><strong><em>J. Biol. Chem.<\/em><\/strong>, 300, 105542 (2024) <a href=\"https:\/\/doi.org\/10.1016\/j.jbc.2023.105542\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1016\/j.jbc.2023.105542<\/a><\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\">-2023 (selected)<\/h4>\n\n\n\n<ol reversed class=\"wp-block-list\">\n<li>A Na pump with reduced stoichiometry is up-regulated by brine shrimp in extreme salinities<br>*Artigas, P., Meyer, D.J., Young, V.C., Spontarelli, K., Eastman, J., Strandquist, E., Rui, H., Roux, B., Brik, M., Nakanishi, H., *<strong><u>Abe, K.<\/u><\/strong> &amp; *Gatto, C.<br><strong><em>Proc. Natl. Acad. Sci. USA.<\/em><\/strong>, 120, e2313999120 (2023) <a href=\"https:\/\/doi.org\/10.1073\/pnas.2313999120\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1073\/pnas.2313999120<\/a><\/li>\n\n\n\n<li>Deep learning driven de novo drug design based on gastric proton pump structures.<br>*<strong><u>Abe K.<\/u><\/strong>, Ozako, M., Inukai, M., Matsuyuki, Y., Kitayama, S., Kanai, C., Nagai, C., Gopalasingam, C.C., Gerle, C., Shigematsu, H., Umekubo, N., *Yokoshima, S. &amp; *Yoshimori, A.<br><strong><em>Commun. Biol.<\/em><\/strong>, 6, 956 (2023) <a href=\"https:\/\/doi.org\/10.1038\/s42003-023-05334-8\">DOI: 10.1038\/s42003-023-05334-8<\/a><\/li>\n\n\n\n<li>Structure and function of H<sup>+<\/sup>\/K<sup>+<\/sup> pump mutants reveal Na<sup>+<\/sup>\/K<sup>+<\/sup> pump mechanism.<br><sup>\u2020<\/sup>Young, V.C., <sup>\u2020<\/sup>Nakanishi, H., Meyer, D.J., Nishizawa, T., Artigas, P. &amp; <strong>*<u>Abe, K.<\/u><\/strong><br><strong><em>Nat. Commun.<\/em><\/strong>, 13, 5270 (2022) <a href=\"https:\/\/doi.org\/10.1038\/s41467-022-32793-0\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1038\/s41467-022-32793-0<\/a><\/li>\n\n\n\n<li>Structural basis for binding of potassium-competitive acid blockers to the gastric proton pump.<br>Tanaka, S., Morita, M., Yamagishi, T., Hridya, V.M., Hayashida, K., Khandelia, H., Gerle, C., Shigematsu, H., Oshima, A. &amp; <strong>*<u>Abe K.<\/u><\/strong><br><strong><em>J. Med. Chem.<\/em><\/strong>, 65, 7843-7853 (2022) <a href=\"https:\/\/doi.org\/10.1021\/acs.jmedchem.2c00338\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1021\/acs.jmedchem.2c00338<\/a><\/li>\n\n\n\n<li>Gastric proton pump with two occluded K<sup>+<\/sup> engineered with sodium pump-mimetic mutations.<br><strong>*<u>Abe, K.<\/u><\/strong>, Yamamoto, K., Irie, K., Nishizawa, T. &amp; Oshima, A.<br><strong><em>Nat. Commun.<\/em><\/strong>, 12, 5709 (2021) <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-26024-1\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1038\/s41467-021-26024-1<\/a><\/li>\n\n\n\n<li>Transport cycle of plasma membrane flippase ATP11C by cryo-EM.<br>Nakanishi, H., Nishizawa, T., Irie, K., Segawa, K., Nureki, O., Fujiyoshi, Y., Nagata, S. &amp;<strong> *<u>Abe, K.<\/u><\/strong><br><strong><em>Cell Rep.<\/em><\/strong>, 32, 108208 (2020) <a href=\"https:\/\/doi.org\/10.1016\/j.celrep.2020.108208\" target=\"_blank\" rel=\"noreferrer noopener\">DOI:&nbsp; 10.1016\/j.celrep.2020.108208<\/a>&nbsp;<\/li>\n\n\n\n<li>A single K<sup>+<\/sup>-binding in the crystal structure of the gastric proton pump.<br>Yamamoto, K., Dubey, V., Irie, K., Nakanishi, H., Khandelia, H., Fujiyoshi, Y. &amp;<strong> *<u>Abe, K.<\/u><\/strong><br><strong><em>eLife<\/em><\/strong>, 8, e47701 (2019) <a href=\"https:\/\/doi.org\/10.7554\/eLife.47701\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.7554\/eLife.47701<\/a><\/li>\n\n\n\n<li>Crystal structures of the gastric proton pump.<br><strong>*<u>Abe, K.<\/u><\/strong>, Irie, K., Nakanishi, H., Suzuki, H. &amp; Fujiyoshi, Y.<br><strong><em>Nature<\/em><\/strong>, 556, 214-218 (2018) <a href=\"https:\/\/doi.org\/10.1038\/s41586-018-0003-8\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1038\/s41586-018-0003-8<\/a><\/li>\n\n\n\n<li>Cryo-EM structure of gastric H<sup>+<\/sup>,K<sup>+<\/sup>-ATPase with a single occupied cation-binding site.<br><strong>*<u>Abe, K.<\/u><\/strong>, Tani, K., Friedrich, T. &amp; Fujiyoshi, Y.<br><strong><em>Proc. Natl. Acad. Sci. USA<\/em><\/strong><em>.<\/em>, 109 (45), 18401-18406 (2012) <a href=\"https:\/\/doi.org\/10.1073\/pnas.1212294109\" target=\"_blank\" rel=\"noreferrer noopener\">DOI: 10.1073\/pnas.1212294109<\/a><\/li>\n\n\n\n<li>Inter-subunit interaction of gastric H<sup>+<\/sup>,K<sup>+<\/sup>-ATPase prevents reverse reaction of the transport cycle.<br><strong><u>Abe, K.<\/u><\/strong>, Tani, K., Nishizawa, T. &amp; *Fujiyoshi, Y.<br><strong><em>EMBO J.<\/em><\/strong>, 28, 1637-1643 (2009) <a href=\"https:\/\/doi.org\/10.1038\/emboj.2009.102\" target=\"_blank\" rel=\"noreferrer noopener\">DOI:&nbsp; 10.1038\/emboj.2009.102<\/a><\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"2\">\u7dcf\u8aac\u30fb\u8457\u66f8<\/h3>\n\n\n\n<ol reversed class=\"wp-block-list\">\n<li>AI\u304c\u63cf\u304f\u80c3\u85ac\u306e\u672a\u6765\u56f3  cryo-EM\u3068Deep Quartet\u304c\u62d3\u304f\u65b0\u305f\u306a\u963b\u5bb3\u5264\u306e\u30c7\u30b6\u30a4\u30f3<br>*\u963f\u90e8\u4e00\u5553\uff0c\u6a2a\u5cf6\u3000\u8061\uff0c\u5409\u68ee\u7be4\u53f2<br>\u5b9f\u9a13\u533b\u5b66\u5897\u520a\uff1a\u69cb\u9020\u751f\u547d\u79d1\u5b66\u3000AlphaFold\u6642\u4ee3\u306b\u3069\u3046\u6d3b\u304b\u3059\uff1f\u301c\u751f\u547d\u6a5f\u80fd\u3092\u89e3\u304f\u3001\u5909\u3048\u308b\u3001\u5275\u308b\u305f\u3081\u306e\u6280\u8853\u3068\u7814\u7a76\u6226\u7565\uff08\u52a0\u85e4\u82f1\u660e\uff0c\u897f\u5897\u5f18\u5fd7\uff0f\u7de8\uff09, Vol.43 No.15, ISBN 978-4-7581-0429-6<\/li>\n\n\n\n<li>Human F-ATP synthase as a drug target<br>Gerle, C., Jiko, C., Nakano, A., Yokoyama, K., Gopalasingam, C.C., Shigematsu, H., *Abe, K.,<br>Pharm Res (2024) DOI:10.1016\/j.phrs.2024.107423<\/li>\n\n\n\n<li>\u7d30\u80de\u819c\u30ea\u30f3\u8102\u8cea\u30d5\u30ea\u30c3\u30d1\u30fc\u30bcATP11C\u306e\u7acb\u4f53\u69cb\u9020\u3068\u8f38\u9001\u6a5f\u69cb.<br>\u4e2d\u897f\u83ef\u4ee3, *\u963f\u90e8\u4e00\u5553<br>\u751f\u5316\u5b66 (2022) DOI: 10.14952\/SEIKAGAKU.2021.930824<\/li>\n\n\n\n<li>\u80c3\u306e\u9178\u6027\u5316\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0.<br>*\u963f\u90e8\u4e00\u5553<br>\u751f\u4f53\u306e\u79d1\u5b66, 71, 310-314 (2020) DOI: 10.11477\/mf.2425201181<\/li>\n\n\n\n<li>\u80c3\u306e\u4e2d\u304c\u5f37\u3044\u9178\u6027\u306b\u306a\u308b\u4ed5\u7d44\u307f.<br>*\u963f\u90e8\u4e00\u5553<br>\u751f\u7269\u7269\u7406, 59, 73-78 (2019) DOI: 10.2142\/biophys.59.073<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"3\">\u5b66\u4f1a\u767a\u8868<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">2025<\/h4>\n\n\n\n<ol reversed class=\"wp-block-list\">\n<li>Abe K. Structural physiology of gastric proton pump and related P-type ATP Pases. A special Seminar at The Victor Chang Cardiac Research Institute, Sydney, 2025\/09\/22, invited<\/li>\n\n\n\n<li>Abe K. Structural basis of the gastric proton pump and related cation pumps &#8211; from mechanism to drug design. The 17th International Meeting on P-Type ATPases in Health &amp; Disease 2025, Cairns, 2025\/09\/18, invited<\/li>\n\n\n\n<li>\u963f\u90e8 \u4e00\u5553, \u80c3\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u306e\u69cb\u9020\u60c5\u5831\u3068 AI \u306b\u3088\u3063\u3066\u99c6\u52d5\u3055\u308c\u305f\u65b0\u898f\u963b\u5bb3\u5264\u306e d5e novo \u30c7\u30b6\u30a4\u30f3, \u7b2c53\u56de\u69cb\u9020\u6d3b\u6027\u76f8\u95a2\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0, 2025\/9\/4, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>Qian Y. Structural Basis of Phospholipid Specificity in ATP11C Q79E. The 1st HU-NYCU DDP Symposium on Chemistry, Sapporo, 2025\/7\/4, Poster presentation<\/li>\n\n\n\n<li>Abe K. AI-driven de novo drug design based on the cryo-EM structure of the gastric proton pump. The 1st HU-NYCU DDP Symposium on Chemistry, Sapporo, 2025\/7\/4<\/li>\n\n\n\n<li>Abe K. Molecular biochemistry of the gastric proton pump and related P-ATPases . IBC seminar, Taipei, 2025\/06\/27, invited<\/li>\n\n\n\n<li>\u963f\u90e8 \u4e00\u5553, \u7d30\u80de\u819c\u8102\u8cea\u30d5\u30ea\u30c3\u30d1\u30fc\u30bcATP11C\u306e\u69cb\u9020\u751f\u7406\u5b66. \u7b2c25\u56de\u65e5\u672c\u86cb\u767d\u8cea\u79d1\u5b66\u4f1a\u5e74\u4f1a, WS3 \u30ea\u30f3\u8102\u8cea\u819c\u3092\u652f\u914d\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u79d1\u5b66\u306e\u30a2\u30f3\u30b5\u30f3\u30d6\u30eb, \u59eb\u8def, 2025\/6\/18, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>Saito H. Development of the sp\u00b3-rich novel acid blocker using cryo-EM and AI-driven drug design platform. 5th Universit\u00e9 de Montr\u00e9al \u2013 Hokkaido University Joint Graduate Student Symposium, Montreal, 2025\/5\/12<\/li>\n\n\n\n<li>Abe K. Molecular biochemistry of the gastric proton pump. Keynote session in CIB symposium, Montreal, 2025\/5\/16, invited<br><\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\">2024<\/h4>\n\n\n\n<ol reversed class=\"wp-block-list\">\n<li>\u963f\u90e8 \u4e00\u5553, \u80fd\u52d5\u8f38\u9001\u4f53P-type ATPase\u306e\u69cb\u9020\u751f\u7406\u5b66. \u4ee4\u548c6(2024)\u5e74\u5ea6\u65e5\u672c\u7d50\u6676\u5b66\u4f1a\u5e74\u4f1a, \u540d\u53e4\u5c4b, 2024\/11\/9, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>\u963f\u90e8 \u4e00\u5553, \u7d30\u80de\u819c\u8102\u8cea\u30d5\u30ea\u30c3\u30d1\u30fc\u30bcATP11C\u306e\u69cb\u9020\u751f\u7406\u5b66. \u7b2c45\u56de\u751f\u4f53\u819c\u3068\u85ac\u7269\u306e\u76f8\u4e92\u4f5c\u7528\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0, \u5fb3\u5cf6, 2024\/10\/10, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>Abe K. Structural physiology of P-type ATPases that generate asymmetric distributions of cations and phospholipids. &#8220;Biased assembly&#8221; in Neuroscience and Cell Biology, Taipei, 2024\/9\/23, invited<\/li>\n\n\n\n<li>\u963f\u90e8 \u4e00\u5553, \u80fd\u52d5\u8f38\u9001\u4f53 P-type ATPase\u306e\u69cb\u9020\u751f\u7406\u5b66. \u751f\u7406\u5b66\u7814\u7a76\u6240 \u7814\u7a76\u4f1a, \u5ca1\u5d0e, 2024\/9\/2, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>Abe K. Structural physiology of gastric proton pump and related cation pumps. The 15th CSE International Summer School &amp; The 12th ALP International Symposium, Shinshinotsu, 2024\/8\/24, invited<\/li>\n\n\n\n<li>QIAN Y. Molecular insights into phospholipid recognition by P4-ATPase flippase. \u7b2c61\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5317\u6d77\u9053\u652f\u90e8\u4f8b\u4f1a, \u672d\u5e4c, 2024\/7\/20, \u30dd\u30b9\u30bf\u30fc\u767a\u8868<\/li>\n\n\n\n<li>Zhang P. Structural analysis of molecular activation mechanism of scramblase Xkr4. \u7b2c61\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5317\u6d77\u9053\u652f\u90e8\u4f8b\u4f1a, \u672d\u5e4c, 2024\/7\/20, \u30dd\u30b9\u30bf\u30fc\u767a\u8868<\/li>\n\n\n\n<li>\u963f\u90e8\u4e00\u5553, \u80fd\u52d5\u8f38\u9001\u4f53 P-type ATPase\u306e\u5206\u5b50\u751f\u547d\u5316\u5b66. \u7b2c61\u56de\u65e5\u672c\u751f\u5316\u5b66\u4f1a\u5317\u6d77\u9053\u652f\u90e8\u4f8b\u4f1a, \u672d\u5e4c, 2024\/7\/20, \u7279\u5225\u8b1b\u6f14<\/li>\n\n\n\n<li>Abe K. Structural physiology of gastric proton pump and related cation pumps. IUPAB2024, Kyoto, 2024\/6\/24, invited <\/li>\n\n\n\n<li>\u963f\u90e8\u4e00\u5553, \u80c3\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u306e\u30af\u30e9\u30a4\u30aa\u96fb\u9855\u69cb\u9020\u306b\u57fa\u3065\u3044\u305fAI\u306b\u3088\u308b\u65b0\u898f\u85ac\u5264\u306e\u30c7\u30b6\u30a4\u30f3. \u7b2c80\u56de\u9855\u5fae\u93e1\u5b66\u4f1a, \u5343\u8449, 2024\/6\/4, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>\u963f\u90e8\u4e00\u5553, \u30ab\u30c1\u30aa\u30f3\u80fd\u52d5\u8f38\u9001\u4f53\u306e\u69cb\u9020\u751f\u7406\u5b66\u3068\u5275\u85ac. \u7b2c101\u56de\u65e5\u672c\u751f\u7406\u5b66\u4f1a\u5927\u4f1a, \u5317\u4e5d\u5dde, 2024\/3\/28, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>\u963f\u90e8\u4e00\u5553, \u69cb\u9020\u89e3\u6790\u306b\u3088\u308b\u80c3\u306e\u9178\u6027\u5316\u30e1\u30ab\u30cb\u30ba\u30e0\u3068AI\u3092\u5229\u7528\u3057\u305f\u80c3\u9178\u6291\u5236\u5264\u306e\u958b\u767a. \u5faa\u74b0\u5668\u7814\u7a76\u30e6\u30cb\u30c3\u30c8\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0, \u611b\u5a9b\u5927\u533b\u5b66\u90e8, 2024\/2\/29, \u62db\u5f85\u8b1b\u6f14<\/li>\n\n\n\n<li>Abe K. Structural physiology of Gastric proton pump. Lecture Biochemistry Molecular Medicine Special Lecture, KU Leuven, Belgium, 2024\/2\/5, invited<\/li>\n\n\n\n<li>Abe K. Deep learning driven de novo drug design based on gastric proton pump structures. 4th Alpine Conference on Medicinal and Synthetic Chemistry, St. Anton, Austria, 2024\/2\/1, invited<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"4\">\u305d\u306e\u4ed6<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">\u79d1\u7814\u8cbb\u304a\u3088\u3073\u516c\u7684\u52a9\u6210\u91d1<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u79d1\u5b66\u7814\u7a76\u8cbb\u88dc\u52a9\u91d1\u3000\u57fa\u76e4\u7814\u7a76(B)\u300e\u7269\u8cea\u4e0d\u5747\u8861\u5206\u5e03\u5f62\u6210\u539f\u7406\u306e\u7406\u89e3\u3092\u76ee\u6307\u3057\u305f\u80fd\u52d5\u8f38\u9001\u4f53P\u578bATPase\u306e\u69cb\u9020\u6a5f\u80fd\u751f\u7406\u5b66\u300f\u7814\u7a76\u4ee3\u8868\u8005, 2024\u5e744\u6708\uff5e2027\u5e743\u6708<\/li>\n\n\n\n<li>\u6226\u7565\u7684\u5275\u9020\u7814\u7a76\u63a8\u9032\u4e8b\u696d\u3000JST CREST\u300e\u9ad8\u6b21\u69cb\u9020\u4f53\u9023\u95a2\u304c\u5236\u5fa1\u3059\u308b\u8102\u8cea\u30b9\u30af\u30e9\u30f3\u30d6\u30eb\u30b7\u30b9\u30c6\u30e0\u300f\u4e3b\u305f\u308b\u5171\u540c\u7814\u7a76\u8005\uff08\u4ee3\u8868\uff1a\u4eac\u90fd\u5927\u5b66\u3000iCeMS \u9234\u6728\u6df3\uff09, 2022\u5e7410\u6708\uff5e2028\u5e743\u6708<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">\u6c11\u9593\u52a9\u6210\u91d1<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u516c\u76ca\u8ca1\u56e3\u6cd5\u4eba\u7b2c\u4e00\u4e09\u5171\u751f\u547d\u79d1\u5b66\u7814\u7a76\u632f\u8208\u8ca1\u56e3 2022\u5e74\u5ea6\u7814\u7a76\u52a9\u6210\u300e\u69cb\u9020\u30fb\u60c5\u5831\u79d1\u5b66\u3092\u99c6\u4f7f\u3057\u305f\u65b0\u305f\u306a\u80c3\u9178\u6291\u5236\u5264\u306e\u5275\u751f\u300f\u7814\u7a76\u4ee3\u8868\u8005, 2023\u5e741\u6708\uff5e2024\u5e7412\u6708<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u696d\u7e3e \u539f\u8457\u8ad6\u6587 2026 2025 2024 -2023 (selected) \u7dcf\u8aac\u30fb\u8457\u66f8 \u5b66\u4f1a\u767a\u8868 2025 2024 \u305d\u306e\u4ed6 \u79d1\u7814\u8cbb\u304a\u3088\u3073\u516c\u7684\u52a9\u6210\u91d1 \u6c11 &#8230; <\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/pages\/15","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":86,"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/pages\/15\/revisions"}],"predecessor-version":[{"id":1251,"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/pages\/15\/revisions\/1251"}],"wp:attachment":[{"href":"https:\/\/wwwchem.sci.hokudai.ac.jp\/~molbio\/wp-json\/wp\/v2\/media?parent=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}