Kazuyasu Sakaguchi received his Ph.D. in Biochemistry at Kyushu University, Japan. From 1989 to 1999, he worked at National Institutes of Health, National Cancer Institute, USA. He moved to Kyushu University as an Associate Professor in 1999. In 2003, he joined to the Department of Chemistry, Hokkaido University as a full Professor. His recent research has focused on structure and function of tumor suppressor protein p53, especially the tetramer formation of p53, and function and regulation of PPM phosphatase family including PPM1D. His research interest also includes understanding about the principle of Life and development of nanomaterials based on oligomerization and self-assembly.



Tumor Supperessor Protein, Cell Cycle, Differentiation, Canser, Evolution, Oligomerization, Phosphatase, Phosphorylation/Dephospharylation, Anticancer drug, Bionanomaterials


  • The Chemical Society of Japan
  • The Japanese Biochemical Society
  • The Japanese Peptide Society
  • The Japanese Society for Chemical Biology
  • The Japanese Association for Protein Phosphatase Research
  • The American Chemical Society

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