Assis. Prof. Iwai

論文検索 :

Dr. Tomohiro Iwai (Original papers/Review)

Original papers
Polystyrene-Cross-Linking Triphenylphosphine on Porous Monolith: Enhanced Catalytic Activity for Aryl Chloride Cross-Coupling in Biphasic Flow
Matsumoto, H.; Hoshino, Y.; Iwai, T.; Sawamura, M.; Miura, Y.
Ind. Eng. Chem. Res. in press. (DOI: 10.1021/acs.iecr.0c02404)
Ir-Catalyzed Reversible Acceptorless Dehydrogenation/Hydrogenation of N-Substituted and Unsubstituted Heterocycles Enabled by a Polymer-Cross-Linking Bisphosphine
Zhang, D.; Iwai, T.; Sawamura, M.
Org. Lett. 2020, 22, 5240–5245. (DOI: 10.1021/acs.orglett.0c01905).
Polystyrene‐Supported PPh3 in Macroporous Monolith: Effect of Cross‐Linking Degree on Coordination Mode and Catalytic Activity in Pd‐Catalyzed C‐C Cross‐Coupling of Aryl Chlorides
Matsumoto, H.; Hoshino, Y.; Iwai, T.; Sawamura, M.; Miura, Y.
ChemCatChem in press. (DOI: 10.1002/cctc.202000651)
Asymmetric Synthesis of α-Aminoboronates via Rhodium-Catalyzed Enantioselective C(sp3)–H Borylation
Reyes, R. L.; Sato, M.; Iwai T.; Sawamura, M.
J. Am. Chem. Soc. 2020, 142, 589–597. (DOI: 10.1021/jacs.9b12013)
Iridium-Catalyzed Alkene-Selective Transfer Hydrogenation with 1,4-Dioxane as Hydrogen Donor
Zhang, D.; Iwai, T.; Sawamura, M.
Org. Lett. 2019, 21, 5867–5872. (DOI: 10.1021/acs.orglett.9b01989)
Nickel-Catalyzed Decarboxylation of Aryl Carbamates for Converting Phenols into Aromatic Amines.
Nishizawa, A.; Takahira, T.; Yasui, K.; Fujimoto, H.; Iwai, T.; Sawamura, M.; Chatani, N.; Tobisu, M.
J. Am. Chem. Soc. 2019, 141, 7261–7265. (DOI: 10.1021/jacs.9b02751)
Iridium-catalyzed Asymmetric Borylation of Unactivated Methylene C(sp3)–H Bonds.
Reyes, R. L.; Iwai, T.; Maeda, S.; Sawamura, M.
J. Am. Chem. Soc. 2019, 141, 6817–6821. (DOI: 10.1021/jacs.9b01952)
Nickel-Copper-Catalyzed Hydroacylation of Vinylarenes with Acyl Fluorides and Hydrosilanes.
Y. Ueda, T. Iwai, M. Sawamura
Chem. Eur. J. 2019, 25, 9410–9414. (DOI: 10.1002/chem.201900822.)
Heterogeneous Nickel-Catalyzed Cross-Coupling between Aryl Chlorides and Alkyllithiums Using a Polystyrene-Cross-Linking Bisphosphine Ligand
Yamazaki, Y.; Arima, N.; Iwai, T.; Sawamura, M.
Adv. Synth. Catal. 2019, 361, 2250–2254. (DOI: 10.1002/adsc.201801713)
A Polystyrene-Cross-Linking Tricyclohexylphosphine: Synthesis, Characterization and Applications to Pd-Catalyzed Cross-Coupling Reactions of Aryl Chlorides
Arashima, J.; Iwai, T.; Sawamura, M.
Chem. Asian J. 2019, 14, 411–415. (DOI: 10.1002/asia.201801651)
P,P,P’,P’-Tetraethynylated Bisphosphine and P-C-P Pincer Ligands with Bulky End Caps: Synthesis, Coordination Properties and Application to Platinum-Catalyzed 1,8-Enyne Cycloisomerization
Iwai, T.; Shibaike, K.; Sawamura, M.
Chem. Lett. 2018, 47, 1162–1164. (DOI: 10.1246/cl.180501)
Palladium-Catalyzed Asymmetric C(sp3)-H Allylation of 2-Alkylpyridines
Murakami, R.; Sano, K.; Iwai, T.; Taniguchi, T.; Monde, K.; Sawamura, M.
Angew. Chem. Int. Ed. 2018, 57, 9465–9469. (DOI: 10.1002/anie.201802821)
Synthesis, Properties, and Catalytic Application of a Triptycene-Type Borate-Phosphine Ligand
Konishi, S.; Iwai, T.; Sawamura, M.
Organometallics 2018, 37, 1876–1883. (DOI: 10.1021/acs.organomet.8b00113)
Transmission of Point Chirality to Axial Chirality for Strong Circular Dichroism in Triarylmethylium-o,o-dimer
Ishigaki, Y.; Iwai, T.; Hayashi, Y.; Nagaki, A.; Katoono, R.; Fujiwara, K.; Yoshida, J.; Suzuki, T.
Synlett 2018, 29, 2147–2154. (DOI: 10.1055/s-0037-1610190)
Phosphine-Catalyzed Anti-Carboboration of Alkynoates with 9-BBN-Based 1,1-Diborylalkanes: Synthesis and Use of Multi-Substituted g-Borylallylboranes
Yamazaki, A.; Nagao, K.; Iwai, T.; Ohmiya, H.; Sawamura, M.
Angew. Chem. Int. Ed. 201857, 3196–3199. (DOI: 10.1002/anie.201712351)
Nickel-Catalyzed Amination of Aryl Fluorides with Primary Amines

Harada, T.; Ueda, Y.; Iwai, T.; Sawamura, M.
Chem. Commun. 2018, 54, 1718–1721. (DOI: 10.1039/C7CC08181B)
Synthesis of Cyclobutene-Fused Eight-Membered Carbocycles through Gold-Catalyzed Intramolecular Enyne [2+2] Cycloaddition
Iwai, T.; Ueno, M.; Okochi, H.; Sawamura, M.
Adv. Synth. Catal. 2018, 360, 670–675. (DOI: 10.1002/adsc.201701193)
Enantioselective Rh- or Ir-Catalyzed Directed C(sp3)–H Borylation with Phosphoramidite Chiral Ligands
Reyes, R. L.; Harada, T.; Taniguchi, T.; Monde, K.; Iwai, T.; Sawamura, M.
Chem. Lett. 2017, 46, 1747–1750. (DOI: 10.1246/cl.170853)
Polystyrene-Cross-Linking Ortho-Substituted Triphenylphosphines: Synthesis, Coordination Properties, and Application to Pd-Catalyzed Cross-Coupling of Aryl Chlorides.
Iwai, T.; Asano, K.; Harada, T.; Sawamura, M.
Bull. Chem. Soc. Jpn. 2017, 90, 943–949. (DOI: 10.1246/bcsj.20170141).
Asymmetric Synthesis of β-Lactams through Copper-Catalyzed Alkyne–Nitrone Coupling with Prolinol-Phosphine Chiral Ligand.
Takayama, Y.; Ishii, T.; Ohmiya, H.; Iwai, T.; Schwarzer, M. C.; Mori, S.; Taniguchi, T.; Monde, K.; Sawamura, M.
Chem. Eur. J. 2017, 238400–8404. DOI: 10.1002/chem.201702070
A Polystyrene-Cross-Linking Bisphosphine: Controlled Metal Monochelation and Ligand-Enabled First-Row Transition Metal Catalysis.
Iwai, T.; Harada, T.; Shimada, H.; Asano, K.; Sawamura, M.
ACS Catal. 2017, 7, 1681–1692. DOI: 10.1021/acscatal.6b02988
Synthesis, Coordination Properties, and Catalytic Application of Triarylmethane-Monophosphines.
Iwai, T.; Tanaka, R.; Sawamura, M.
Organometallics, 2016, 35, 3959-3969. DOI: 10.1021/acs.organomet.6b00752
Site-selective and Stereoselective C(sp3)–H Borylation of Alkyl Side Chains of 1,3-Azoles with a Silica-Supported Monophosphine-Ir Catalyst.
Murakami, R.; Iwai, T.; Sawamura, M.
Synlett, 2016, 27, 1187-1192. DOI: 10.1055/s-0035-1561599
Silica-supported Triptycene-type Phosphine. Synthesis, Characterization, and Application to Pd-Catalyzed Suzuki–Miyaura Cross-coupling of Chloroarenes.
Iwai, T.; Konishi, S.; Miyazaki, T.; Kawamorita, S.; Yokokawa, N.; Ohmiya, H.; Sawamura, M.
ACS Catal., 2015, 5, 7254–7264. DOI: 10.1021/acscatal.5b00904
Synthesis and Structures of a Chiral Phosphine-Phosphoric Acid Ligand and Its Rhodium(I) Complexes.
Iwai, T.; Akiyama, Y.; Tsunoda, K.; Sawamura, M.
Tetrahedron: Asymmetry, 2015, 26, 1245-1250. DOI: 10.1016/j.tetasy.2015.09.016
Stereoselective C–H Borylations of Cyclopropanes and Cyclobutanes with Silica-supported Monophosphane-Ir Catalysts.
Murakami, R.; Tsunoda, K.; Iwai, T.; Sawamura, M.
Chem. Eur. J. 2014, 20, 13127–13131. DOI: 10.1002/chem.201404362
Silica-Supported Tripod Triarylphosphane: Application to Transition Metal Catalyzed C(sp3)–H Borylations.
Iwai, T.; Murakami, R.; Harada,T.; Kawamorita, S.; Sawamura, M.
Adv. Synth. Catal. 2014, 356, 1563–1570. DOI: 10.1002/adsc.201301147
Silica-supported Tripod Triarylphosphines: Application to Palladium Catalyzed Borylation of Chloroarenes.

Iwai, T.;  Harada, T.; Tanaka, R.; Sawamura, M.
Chem. Lett. 2014, 43, 584–586. DOI: 10.1246/cl.131161
Tripod Immobilization of Triphenylphosphane on a Silica Gel Surface to Enable Selective Mono-P-ligation to Palladium: Application to Suzuki–Miyaura Cross-Coupling with Chloroarenes.
Iwai, T.; Tanaka, R.; Harada, T.; Sawamura, M.
Chem. Eur. J. 2014, 20, 1057–1065. DOI: 10.1002/chem.201304081
Site-selective C–H Borylation of Quinolines at the C-8 Position Catalyzed by a Silica-supported Phosphane-Iridium System.
Konishi, S.; Kawamorita, S.; Iwai, T.; Steel, P. G.; Marder, T. B.; Sawamura, M.
Chem. Asian J. 2014, 9, 434–438. DOI: 10.1002/asia.201301423
Threefold Cross-Linked Polystyrene-Triphenylphosphane Hybrids: Mono-P-Ligating Behaviors and Catalytic Applications for Aryl Chloride Cross-Coupling and C(sp3)–H Borylation.
Iwai, T.; Harada, T.; Hara, K.; Sawamura, M.
Angew. Chem. Int. Ed. 2013, 52, 12322–12326. DOI: 10.1002/anie.201306769
Synthesis of a Chiral N-Heterocyclic Carbene Bearing a m-Terphenyl-Based Phosphate Moiety as an Anionic N-Substituent and Its Application to Copper-Catalyzed Enantioselective Boron Conjugate Addition.
Iwai, T.; Akiyama,Y.; Sawamura, M.
Tetrahedron: Asymmetry 2013, 24, 729–735. DOI: 10.1016/j.tetasy.2013.05.013.
Synthesis of Primary and Secondary Alkylboronates through Site-Selective C(sp3)–H Activation with Silica-Supported Monophosphine–Ir Catalysts
Kawamorita, S.; Murakami, R; Iwai, T.; Sawamura, M.
J. Am. Chem. Soc. 2013, 135, 2947–2950. DOI: 10.1021/ja3126239
Construction of Eight-Membered Carbocycles via Gold Catalysis with Acetylene-Tethered Silyl Enol Ethers.
Iwai, T.; Okochi,H.; Ito, H.; Sawamura, M.
Angew. Chem. Int. Ed. 2013, 52, 4239-4242. DOI: 10.1002/anie.201300265
7,7,8,8-Tetraaryl-o-quinodimethane Stabilized by Dibenzo-annulation: A Helical pi-Electron System that Exhibits Electrochromic and Unique Chiroptical Properties
Suzuki, T.; Sakano, Y.; Iwai, T.; Iwashita, S.; Miura, Katoono, R.; Kawai, H.; Fujiwara, K.; Tsuji, Y.; Fukushima, T.
Chem. Eur. J. 2013, 19, 117–123. DOI: 10.1002/chem.201203092
Conjugate Reduction of a,b-Unsaturated Carbonyl and Carboxyl Compounds with Poly(methylhydrosiloxane) Catalyzed by a Silica-Supported Compact Phosphane–Copper Complex.
Kawamorita, S.; Yamazaki, K.; Ohmiya, H.; Iwai, T.;  Sawamura, M.
Adv. Synth. Catal. 2012, 354, 3440–3444. DOI: 10.1002/adsc.201200555
Palladium-Catalyzed Reduction of Acid Chlorides to Aldehydes with Hydrosilanes
Fujihara, T.; Cong, C.; Iwai, T.; Terao, J.; Tsuji, Y.
Synlett 2012, 23, 2389–2392. DOI: 10.1055/s-0032-1317155
Rh-Catalyzed Borylation of N–Adjacent C(sp3)–H Bonds with a Silica-Supported Triarylphosphine Ligand.
Kawamorita, S.; Miyazaki, T.; Iwai, T.; Ohmiya, H.;  Sawamura, M.
J. Am. Chem. Soc. 2012, 134, 12924–12927. DOI: 10.1021/ja305694r
Palladium-catalyzed esterification of aryl halides using aryl formates without the use of external carbon monoxide.
Fujihara, T.; Hosoki, T.; Katafuchi, Y.; Iwai, T.; Terao, J.; Tsuji, Y.
Chem. Commun. 2012, 48, 8012–8014. DOI: 10.1039/C2CC33944G
Iridium-Catalyzed Addition of Aroyl Chlorides and Aliphatic Acid Chlorides to Terminal Alkynes.
Iwai, T.; Fujihara, T.; Terao, J.; Tsuji, Y.
J. Am. Chem. Soc. 2012, 134, 1268-1274. DOI: 10.1021/ja209679c
Rh-Catalyzed Ortho-Selective C-H Borylation of N-Functionalized Arenes with Silica-Supported Bridgehead Monophosphine Ligands.
Kawamorita, S.; Miyazaki, T.; Ohmiya, H.; Iwai, T.; Sawamura, M.
J. Am. Chem. Soc
. 2011, 133, 19310-19313. DOI: 10.1021/ja208364a
Palladium-Catalyzed Borylation of Sterically Demanding Aryl Halides with Silica-Supported Compact Phosphane Ligand.
Kawamorita, S.; Ohmiya, H.; Iwai, T.; Sawamura, M.
Angew. Chem. Int. Ed. (VIP)
2011, 50, 8363-8366. DOI: 10.1002/anie.201103224
Palladium-Catalyzed Hydroesterification of Alkynes Employing Aryl Formates without the Use of External Carbon Monoxide
Katafuchi, Y.; Fujihara, T.; Iwai, T.; Terao, J.; Tsuji, Y.
Adv. Synth. Catal
. 2011, 353, 475-482. DOI: 10.1002/adsc.201000750
Iridium-Catalyzed Annulation of N-Arylcarbamoyl Chlorides with Internal Alkynes
Iwai, T.; Fujihara, T.; Terao, J.; Tsuji, Y.
J. Am. Chem. Soc
. 2010, 132, 9602-9603. DOI: 10.1021/ja104153k
Palladium-Catalyzed Intermolecular Addition of Formamides to Alkynes
Fujihara, T.; Katafuchi, Y.; Iwai, T.; Terao, J.; Tsuji, Y.
J. Am. Chem. Soc. 2010, 132, 2094-2098. DOI: 10.1021/ja910038p
Multi-Input/Multi-Output Molecular Response System Based on the Dynamic Redox Behavior of 3,3,4,4-Tetraaryldihydro[5]helicene Derivatives: Reversible Formation/Destruction of Chiral Fluorophore and Modulation of Chiroptical Properties by Solvent Polarity
Suzuki, T.; Ishigaki, Y.; Iwai, T.; Kawai, H.; Fujiwara, K.; Ikeda, H.; Kano, Y.; Mizuno, K.
Chem. Eur. J
. 2009, 15, 9434-9441. DOI: 10.1002/chem.200900968
Iridium-Catalyzed Addition of Acid Chlorides to Terminal Alkynes
Iwai, T.; Fujihara, T.; Terao, J.; Tsuji, Y.
J. Am. Chem. Soc. 2009, 131, 6668-6669. DOI: 10.1021/ja901778y
The Iridium-Catalyzed Decarbonylation of Aldehydes under Mild Conditions
Iwai, T.; Fujihara, T.; Tsuji, Y.
Chem. Commun
. 2008, 6215-6217. DOI: 10.1039/b813171f
Electrochiroptical systems based on biphenyl-2,2'-diyl-type dicationic dyes: Strong chiroptical signals through the transmission of point chirality to axial chirality
Suzuki, T.; Iwai, T.; Ohta, E.; Kawai, H.; Fujiwara, K.
Tetrahedron Lett
. 2007, 48, 3599-3603. DOI: 10.1016/j.tetlet.2007.03.080 
A Bowl-Shaped Phosphine as a Ligand in Palladium-Catalyzed Suzuki-Miyaura Coupling of Aryl Chlorides: Effect of a Depth of the Bowl
Ohta, H.; Tokunaga, M.; Obora, Y.; Iwai, T.; Iwasawa, T.; Fujihara, T.; Tsuji, Y.
Org. Lett. 2007, 9, 89-92. DOI: 10.1021/ol0626138
触媒技術の動向と展望2019, 触媒学会(編), 113–123 (2019).
岩井 智弘
触媒, 201759, 102-103.
岩井 智弘
化学, 2016, 71, 59-60.
Redox-Mediated Reversible σ-Bond Formation/Cleavage.
Suzuki, T.; Tamaoki, H.; Nishida, J.; Higuchi, H.; Iwai, T.; Ishigaki, Y.; Hanada, K.; Katoono, R.; Kawai, H.; Fujiwara, K.; Fukushima, T. in Organic Redox Systems: Synthesis, Properties, and Applications;
Nishinaga, T. Ed.; Wiley, Chapter 2, pp. 13–37, 2016DOI: 10.1002/9781118858981.ch2
Transition-metal-catalyzed Site-selective C–H Functionalization of Quinolines beyond C2 Selectivity.
Iwai, T.; Sawamura, M.
ACS Catal. 2015, 5, 5031–5040. DOI: 10.1021/acscatal.5b01143
Transition Metal Catalysis with Hollow-shaped Triethynylphosphine Ligands.
Iwai, T.; Sawamura, M.
Bull. Chem. Soc. Jpn. 2014, 87, 1147–1160. (Award Account) DOI: 10.1246/bcsj.20140186
岩井 智弘
有機合成化学協会誌, vol. 72, pp 68–69, 2014.
Electrochromic and unique chiroptical properties of helically deformed tetraarylquinodimethanes generated from less hindered dicationic precursors upon reduction
Suzuki, T.; Sakano, Y.; Iwai, T.; Iwashita, S.; Miura, Y.; Katoono, R.;  Kawai, H.; Fujiwara, K.; Tsuji, Y.; Fukushima, T.
Pure Appl. Chem. 2014, 86, 507. DOI: 10.1515/pac-2013-1003
Transition-Metal-Catalyzed Additions of Carbonyl Functionalities to Alkynes
Fujihara, T.; Iwai, T.; Terao, J.; Tsuji, Y.
2010, 2537-2548. DOI: 10.1055/s-0030-1258776